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Meriva (curcumin-phosphatidylcholine phytosome complex): Osteoarthritis

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By: Sean Moloughney

Editor, Nutraceuticals World

Nutraceutical: Meriva (curcumin-phosphatidylcholine phytosome complex)
 
Indication: Osteoarthritis
 
Source: Altern Med Rev, December 2010;15(4):337-44.
 
Research: In a previous 3-month study of Meriva, a proprietary curcumin-phosphatidylcholine phytosome complex, decreased joint pain and improvement in joint function were observed in 50 osteoarthritis (OA) patients. Since OA is a chronic condition requiring prolonged treatment, the long-term efficacy and safety of Meriva were investigated in a longer 8-month study involving 100 OA patients. The clinical endpoints (Western Ontario and McMaster Universities [WOMAC] score, Karnofsky Performance Scale Index, and treadmill walking performance) were complemented by the evaluation of a series of inflammatory markers.
 
Results: This study represents the most ambitious attempt, to date, to evaluate the clinical efficacy and safety of curcumin as an anti-inflammatory agent. Significant improvements of both the clinical and biochemical endpoints were observed for Meriva compared to the control group. This, coupled with an excellent tolerability, suggests that Meriva is worth considering for the long-term complementary management of osteoarthritis.
 

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